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DrNote Library
Rheumatology
9 articles
- RheumatologyAntiphospholipid SyndromeAntiphospholipid syndrome (APS) is an acquired autoimmune thrombophilia defined clinically by arterial, venous, or microvascular thrombosis and/or characteristic pregnancy morbidity together with persistent antiphosph…11 min read
- RheumatologyGiant Cell ArteritisGiant cell arteritis (GCA) is an immune-mediated granulomatous vasculitis of medium and large arteries that occurs almost exclusively in adults aged 50 years or older. It commonly affects branches of the external caro…26 min read
- RheumatologyGoutGout is an inflammatory crystal arthritis caused by deposition of monosodium urate (MSU) crystals in joints and periarticular tissues. Hyperuricemia promotes crystal formation but does not by itself establish gout. Du…13 min read
- RheumatologyOsteoarthritisOsteoarthritis (OA) is a whole-joint disorder involving cartilage, subchondral bone, synovium, ligaments, menisci or labrum, capsule, and periarticular muscle. It causes activity-related pain, brief stiffness, functio…11 min read
- RheumatologyPolymyalgia RheumaticaPolymyalgia rheumatica (PMR) is an inflammatory syndrome of adults aged 50 years or older characterized by bilateral shoulder-girdle pain and marked morning stiffness, often with hip-girdle or neck symptoms and elevat…15 min read
- RheumatologyPrimary Sjögren DiseasePrimary Sjögren disease is a chronic systemic autoimmune disorder characterized by lymphocytic injury to exocrine glands, most prominently the lacrimal and salivary glands, with frequent extraglandular disease. Dry ey…12 min read
- RheumatologyRheumatoid ArthritisRheumatoid arthritis (RA) is a chronic immune-mediated inflammatory arthritis characterized by persistent synovitis with potential for erosive joint damage, tendon injury, deformity, disability, and systemic disease.…15 min read
- RheumatologySystemic Lupus ErythematosusSystemic lupus erythematosus (SLE) is a chronic autoimmune disease with highly variable involvement of skin, joints, blood cells, kidneys, nervous system, lungs, heart, and blood vessels. Diagnosis is clinical and req…13 min read
- RheumatologySystemic SclerosisSystemic sclerosis (SSc) is a heterogeneous autoimmune connective-tissue disease characterized by vasculopathy, immune dysregulation, and progressive fibrosis of skin and internal organs. The two major cutaneous subse…16 min read